Table 4: Dilution linearity of plasma protein.

Sample/Dilution

J-357 digital

TS-D digital

Goldberg TS

mg/mL a)

mg/mL a)

mg/mL SP (direct) b)

mg/mL SP (20 °C) c)

mg/mL SP d)

Permeate

0.0

0

7

9 (23.7 °C)

ND

0.10

16.8

17

21

22 (22.6 °C)

~ 20

0.15

25.2

26

26

28 (23.0 °C)

26

0.20

34.0

34

35

37 (23.3 °C)

35

0.30

49.6

49

51

53 (23.4 °C)

51

0.40

66.5

66

67

70 (23.8 °C)

68

0.50

82.9

82

84

86 (23.8 °C)

85

0.60

99.3

98

100

102 (23.9 °C)

102

0.70

115.9

115

117

119 (24.1 °C)

118

0.80

132.4

131

133

136 (24.1 °C)

136

0.90

150.4

150

152

155 (24.2 °C)

~ 154

Concentrate

168.3

169

171

173 (24.3)

ND

Remarks: ND stands for not determined, SP for serum protein: a) Calculated protein concentrations using the dn/dc value of 0.000192 for the permeate-corrected RI values; b) Serum protein concentrations as calculated by the instrument without temperature and permeate correction; c) Serum protein concentrations as obtained after temperature compensation automatically done by the instrument. Numbers in brackets show the temperature actually measured; d) Serum protein concentrations as obtained by the Goldberg TS device.